D. Bladeren : rechercher sur Z-Library

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1

Glutathione conjugation as a bioactivation reaction

Peter J van Bladeren

Journal:

Chemico-Biological Interactions

Année:

2000

Langue:

english

Fichier:

PDF, 146 KB

english, 2000

2

In Vivo and in Vitro Metabolic Studies of Furazolidone: A Risk Evaluation

Vroomen, Louis H. M., Berghmans, Marcel C. J., Van Bladeren, Peter J., Groten, John P., Wissink, C. J., Kuiper, Harry A.

Journal:

Drug Metabolism Reviews

Année:

1990

Langue:

english

Fichier:

PDF, 999 KB

english, 1990

3

Identification of a reactive intermediate of furazolidone formed by swine liver microsomes

Louis H.M. Vroomen, John P. Groten, Kees van Muiswinkel, Albertus van Velduizen, Peter J. van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1987

Langue:

english

Fichier:

PDF, 700 KB

english, 1987

4

Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity

Anne-Marie J.F. Boerboom, Martijn Vermeulen, Hester van der Woude, Birgit I. Bremer, Yee Y. Lee-Hilz, Ellen Kampman, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Jac M.M.J.G. Aarts

Journal:

Biochemical Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 281 KB

english, 2006

5

Subacute Toxicity of a Mixture of Nine Chemicals in Rats: Detecting Interactive Effects with a Fractionated Two-Level Factorial Design

John P. Groten, Eric D. Schoen, Peter J. van Bladeren, C.Frieke Kuper, Job A. van Zorge, Victor J. Feron

Journal:

Fundamental and Applied Toxicology

Année:

1997

Langue:

english

Fichier:

PDF, 136 KB

english, 1997

6

4-Week oral toxicity study of a combination of eight chemicals in rats: Comparison with the toxicity of the individual compounds

D. Jonker, R.A. Woutersen, P.J. van Bladeren, H.P. Til, V.J. Feron

Journal:

Food and Chemical Toxicology

Année:

1990

Langue:

english

Fichier:

PDF, 720 KB

english, 1990

7

Acute (24 hr) toxicity of a combination of four nephrotoxicants in rats compared with the toxicity of the individual compounds

D. Jonker, M.A. Jones, P.J. van Bladeren, R.A. Woutersen, H.P. Til, V.J. Feron

Journal:

Food and Chemical Toxicology

Année:

1993

Langue:

english

Fichier:

PDF, 717 KB

english, 1993

8

Subacute (4-wk) oral toxicity of a combination of four nephrotoxins in rats: comparison with the toxicity of the individual compounds

D. Jonker, R.A. Woutersen, P.J. Van Bladeren, H.P. Til, V.J. Feron

Journal:

Food and Chemical Toxicology

Année:

1993

Langue:

english

Fichier:

PDF, 969 KB

english, 1993

9

Subacute Toxicity of a Mixture of Nine Chemicals in Rats: Detecting Interactive Effects with a Fractionated Two-Level Factorial Design

GROTEN, JOHN P., SCHOEN, ERIC D., VAN BLADEREN, PETER J., KUPER, C. FRIEKE, VAN ZORGE, JOB A., FERON, VICTOR J.

Journal:

Toxicological Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 1.21 MB

english, 1997

10

Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model

Martin, Francois-Pierre J, Wang, Yulan, Sprenger, Norbert, Yap, Ivan K S, Rezzi, Serge, Ramadan, Ziad, Peré-Trepat, Emma, Rochat, Florence, Cherbut, Christine, van Bladeren, Peter, Fay, Laurent B, Koc

Journal:

Molecular Systems Biology

Année:

2008

Langue:

english

Fichier:

PDF, 647 KB

english, 2008

11

Identification of multiple target sites for a glutathione conjugate on glutathione-S-transferase by matrix-assisted laser desorption/ionization mass spectrometry

Jespersen, S., Ploemen, J. H. T. M., van Bladeren, P. J., Niessen, W. M. A., Tjaden, U. R., van der Greef, J.

Journal:

Journal of Mass Spectrometry

Année:

1996

Langue:

english

Fichier:

PDF, 576 KB

english, 1996

12

Interaction of hesperetin glucuronide conjugates with human BCRP, MRP2 and MRP3 as detected in membrane vesicles of overexpressing baculovirus-infected Sf9 cells

Walter Brand, Berend Oosterhuis, Peter Krajcsi, Denis Barron, Fabiola Dionisi, Peter J. van Bladeren, Ivonne M. C. M. Rietjens, Gary Williamson

Journal:

Biopharmaceutics & Drug Disposition

Année:

2011

Langue:

english

Fichier:

PDF, 215 KB

english, 2011

13

Electron impact and chemical ionization mass spectrometry of cis- and trans-S-(2-hydroxyclohexyl)-N-acetyl-(l)-cysteine methyl esters

N. P. E. Vermeulen, J. Cauvet, W. C. M. M. Luijten, P. J. van Bladeren

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Année:

1980

Langue:

english

Fichier:

PDF, 422 KB

english, 1980

14

The effect of co-administered flavonoids on the metabolism of hesperetin and the disposition of its metabolites in Caco-2 cell monolayers

Walter Brand, Beatriz Padilla, Peter J. van Bladeren, Gary Williamson, Ivonne M. C. M. Rietjens

Journal:

Molecular Nutrition & Food Research

Année:

2010

Langue:

english

Fichier:

PDF, 303 KB

english, 2010

15

In silico methods for physiologically based biokinetic models describing bioactivation and detoxification of coumarin and estragole: Implications for risk assessment

Ivonne M. C. M. Rietjens, Ans Punt, Benoît Schilter, Gabriele Scholz, Thierry Delatour, Peter J. van Bladeren

Journal:

Molecular Nutrition & Food Research

Année:

2010

Langue:

english

Fichier:

PDF, 331 KB

english, 2010

16

Toxicology of chemical mixtures: challenges for today and the future

V.J. Feron, J.P. Groten, D. Jonker, F.R. Cassee, P.J. van Bladeren

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 1.31 MB

english, 1995

17

Transport and metabolism of glutathione conjugates of menadione and ethacrynic acid in confluent monolayers of rat renal proximal tubular cells

H.E.M.G. Haenen, A. Spenkelink, C. Teunissen, J.H.M. Temmink, J.H. Koemana, P.J. van Bladeren

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1996

18

Chemical and enzyme-catalysed synthesis of quinoline arene hydrates

Rajiv Agarwal, Derek R. Boyd, Narain D. Sharma, R. Austin, S. McMordie, H.Patricia Porter, Ben van Ommen, Peter J. van Bladeren

Journal:

Bioorganic & Medicinal Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 1006 KB

english, 1994

19

Genomic tools to study biological effects of food

P. van-Bladeren

Journal:

Journal of Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 122 KB

english, 2010

20

An improved method for the separation and quantification of glutathione S-transferase subunits in rat tissue using high-performance liquid chromatography

Jan J.P. Bogaards, Ben van Ommen, Peter J. van Bladeren

Journal:

Journal of Chromatography A

Année:

1989

Langue:

english

Fichier:

PDF, 366 KB

english, 1989

21

Facile synthesis of K-region arene oxides

P.J. van Bladeren, D.M. Jerina

Journal:

Tetrahedron Letters

Année:

1983

Langue:

english

Fichier:

PDF, 257 KB

english, 1983

22

Cytomorphological changes in liver cells exposed to allyl and benzyl isothiocyanate and their cysteine and glutathione conjugates

J. H. M. Temmink, I. M. Bruggeman, P. J. Bladeren

Journal:

Archives of Toxicology

Année:

1986

Langue:

english

Fichier:

PDF, 4.13 MB

english, 1986

23

Oxidative biotransformation in primary cultures of chick embryo hepatocytes: induction of cytochrome P-450 and the metabolism of benzo(a)pyrene

R. J. Topp, P. J. Bladeren

Journal:

Archives of Toxicology

Année:

1986

Langue:

english

Fichier:

PDF, 619 KB

english, 1986

24

The dual role of glutathione conjugation in the biotransformation of xenobiotics. A multidisciplinary investigation

P. J. Van Bladeren

Journal:

International Journal of Clinical Pharmacy

Année:

1982

Langue:

english

Fichier:

PDF, 176 KB

english, 1982

25

Genetic deficiency of human class mu glutathione S-transferase isoenzymes in relation to the urinary excretion of the mercapturic acids of Z- and E-1,3-dichloropropene

Ria M. E. Vos, Ronald T. H. van Welie, Wilbert H. M. Peters, Chris T. A. Evelo, Jan J. P. Boogaards, Nico P. E. Vermeulen, Peter J. van Bladeren

Journal:

Archives of Toxicology

Année:

1991

Langue:

english

Fichier:

PDF, 562 KB

english, 1991

26

Sectievergaderingen

A. J. M. M. Beysens, D. Bladeren, J. H. Zwaving, H. A. Sloot, J. Bron, J. F. Jonckers, J. Winters, K. E. Hagenaar, A. W. M. Indemans, A. Bult

Journal:

International Journal of Clinical Pharmacy

Année:

1981

Langue:

dutch

Fichier:

PDF, 2.40 MB

dutch, 1981

27

Militaire apothekers

D. van Bladeren

Journal:

International Journal of Clinical Pharmacy

Année:

1980

Langue:

dutch

Fichier:

PDF, 572 KB

dutch, 1980

28

Sectievergaderingen

P. H. Vree, D. Van Bladeren, H. A. Sloot, A. W. M. Indemans

Journal:

International Journal of Clinical Pharmacy

Année:

1979

Langue:

dutch

Fichier:

PDF, 1.02 MB

dutch, 1979

29

Uw patiënt rookt, wat nu?

Fleur van Bladeren, Ingrid Stevens

Journal:

Nederlands Tijdschrift voor Evidence Based Practice

Année:

2007

Langue:

dutch

Fichier:

PDF, 113 KB

dutch, 2007

30

Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer–related mechanisms in colon cancer cells in vitro

M. J. van Erk, P. Roepman, T. R. van der Lende, R. H. Stierum, J. M. M. J. G. Aarts, P. J. van Bladeren, B. van Ommen

Journal:

European Journal of Nutrition

Année:

2005

Langue:

english

Fichier:

PDF, 360 KB

english, 2005

31

Glutathione S-transferase activity and isoenzyme composition in benign ovarian tumours, untreated malignant ovarian tumours, and malignant ovarian tumours after platinum/cyclophosphamide chemotherapy

van der Zee, AGJ, van Ommen, B, Meijer, C, Hollema, H, van Bladeren, PJ, de Vries, EGE

Journal:

British Journal of Cancer

Année:

1992

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1992

32

Structure−Activity Study on the Quinone/Quinone Methide Chemistry of Flavonoids

Awad, Hanem M., Boersma, Marelle G., Boeren, Sjef, van Bladeren, Peter J., Vervoort, Jacques, Rietjens, Ivonne M. C. M.

Journal:

Chemical Research in Toxicology

Année:

2001

Langue:

english

Fichier:

PDF, 127 KB

english, 2001

33

Quenching of Quercetin Quinone/Quinone Methides by Different Thiolate Scavengers: Stability and Reversibility of Conjugate Formation

Awad, Hanem M., Boersma, Marelle G., Boeren, Sjef, van Bladeren, Peter J., Vervoort, Jacques, Rietjens, Ivonne M. C. M.

Journal:

Chemical Research in Toxicology

Année:

2003

Langue:

english

Fichier:

PDF, 190 KB

english, 2003

34

Regioselectivity of Phase II Metabolism of Luteolin and Quercetin by UDP-Glucuronosyl Transferases

Boersma, Marelle G., van der Woude, Hester, Bogaards, Jan, Boeren, Sjef, Vervoort, Jacques, Cnubben, Nicole H. P., van Iersel, Marlou L. P. S., van Bladeren, Peter J., Rietjens, Ivonne M. C. M.

Journal:

Chemical Research in Toxicology

Année:

2002

Langue:

english

Fichier:

PDF, 95 KB

english, 2002

35

A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids

Beekmann, Karsten, Actis-Goretta, Lucas, van Bladeren, Peter J., Dionisi, Fabiola, Destaillats, Frederic, Rietjens, Ivonne M. C. M.

Journal:

Food & Function

Année:

2012

Langue:

english

Fichier:

PDF, 160 KB

english, 2012

36

Physiologically Based Biokinetic (PBBK) Modeling of Safrole Bioactivation and Detoxification in Humans as Compared With Rats

Martati, E., Boersma, M. G., Spenkelink, A., Khadka, D. B., van Bladeren, P. J., Rietjens, I. M. C. M., Punt, A.

Journal:

Toxicological Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 2.13 MB

english, 2012

37

Use of Physiologically Based Biokinetic (PBBK) Modeling to Study Estragole Bioactivation and Detoxification in Humans as Compared with Male Rats

Punt, A., Paini, A., Boersma, M. G., Freidig, A. P., Delatour, T., Scholz, G., Schilter, B., Bladeren, P. J. v., Rietjens, I. M. C. M.

Journal:

Toxicological Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 364 KB

english, 2009

38

Tandem Mass Spectrometry Analysis of N2-(trans-Isoestragol-3‘-yl)-2‘-deoxyguanosine as a Strategy to Study Species Differences in Sulfotransferase Conversion of the Proximate Carcinogen 1‘-Hydroxyestragole

Punt, Ans, Delatour, Thierry, Scholz, Gabriele, Schilter, Benoît, van Bladeren, Peter J., Rietjens, Ivonne M. C. M.

Journal:

Chemical Research in Toxicology

Année:

2007

Langue:

english

Fichier:

PDF, 117 KB

english, 2007

39

A Physiologically Based Pharmacokinetic (PB-PK) Model for 1,2-Dichlorobenzene Linked to Two Possible Parameters of Toxicity

A.M. Hissink, B. Van Ommen, J. Krüse, P.J. Van Bladeren

Journal:

Toxicology and Applied Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 159 KB

english, 1997

40

Species and Strain Differences in the Hepatic Cytochrome P450-Mediated Biotransformation of 1,4-Dichlorobenzene

A.M. Hissink, M.J. Oudshoorn, B. Van Ommen, P.J. Van Bladeren

Journal:

Toxicology and Applied Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 143 KB

english, 1997

41

The microsomal metabolism of pentachlorophenol and its covalent binding to protein and DNA

Ben van Ommen, Anton Adang, Franz Müller, Peter J. van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1986

Langue:

english

Fichier:

PDF, 595 KB

english, 1986

42

The role of glutathione and glutathione S-transferases in fatty acid ozonide detoxification

I.M.C.M. Rietjens, H.H. Lemmink, G.M. Alink, P.J. Van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1987

Langue:

english

Fichier:

PDF, 694 KB

english, 1987

43

Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-pentachlorobutadienyl)glutathione and N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine

Jos J.W.M. Mertens, John G.J. Weijnen, Wim J. Van Doorn, Bert Spenkelink, Johan H.M. Temmink, Peter J. Van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1988

Langue:

english

Fichier:

PDF, 627 KB

english, 1988

44

The oxidation of tetrachloro-1,4-hydroquinone by microsomes and purified cytochrome P-450b. Implications for covalent binding to protein and involvement of reactive oxygen species

Ben van Ommen, Jan Willem Voncken, Franz Müller, Peter J. van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1988

Langue:

english

Fichier:

PDF, 736 KB

english, 1988

45

Methyl linoleate ozonide as a substrate for rat glutathione S-transferases: Reaction pathway and isoenzyme selectivity

Ria M.E. Vos, Ivonne M.C.M. Rietjens, Luc H. Stevens, Peter J. Van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1989

Langue:

english

Fichier:

PDF, 528 KB

english, 1989

46

Cytotoxicity of S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine after apical and basolateral exposure of LLC-PK1 monolayers. Involvement of an amino acid transport system

Jos J.W.M. Mertens, Erik A.J. Keukens, Marco Appel, Bert Spenkelink, Johan H.M. Temmink, Peter J. van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1990

Langue:

english

Fichier:

PDF, 663 KB

english, 1990

47

Irreversible inhibition of rat hepatic glutathione S-transferase isoenzymes by a series of structurally related quinones

Ria M.E. Vos, Ben Van Ommen, Mark S.J. Hoekstein, Jolanda H.M. De Goede, Peter J. Van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1989

Langue:

english

Fichier:

PDF, 637 KB

english, 1989

48

Glutathione S-transferases in relation to their role in the biotransformation of xenobiotics

Ria M.E. Vos, Peter J. Van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1990

Langue:

english

Fichier:

PDF, 1.44 MB

english, 1990

49

The involvement of primary and secondary metabolism in the covalent binding of 1,2- and 1,4-dichlorobenzenes

Cathaline den Besten, Marlies Ellenbroek, Marjan A.E. van der Ree, Ivonne M.C.M. Rietjens, Peter J. van Bladeren

Journal:

Chemico-Biological Interactions

Année:

1992

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1992

50

Metabolism and biochemical effects of 3,3′,4,4′-tetrachlorobiphenyl in pregnant and fetal rats

Dennis C. Morse, Eva Klasson Wehler, Maribel van de Pas, Albert Th.H.J. de Bie, Peter J. van Bladeren, Abraham Brouwer

Journal:

Chemico-Biological Interactions

Année:

1995

Langue:

english

Fichier:

PDF, 1.22 MB

english, 1995